Simon Holzinger

I am a sequencing expert and bioinformatician with a particular interest in the intricate mechanisms of DNA packaging. My research aims to elucidate the mechanisms underlying nucleosome positioning and its function in chromatin organisation and transcriptional regulation.

 

I undertook my undergraduate and postgraduate studies in Biochemistry at the University of Regensburg, specialising in sequencing technologies and genomics analysis. During my doctoral studies in the laboratory of Gernot Längst, I investigated the role of individual histone tails in chromatin organisation and nucleosome positioning. Additionally, I contributed to research exploring chromatin architecture in a range of other organisms, including Plasmodium falciparum, adenovirus and SARS-CoV-2. Since completing my PhD, I have concentrated my research efforts on elucidating the unique chromatin landscape of the malaria parasite, utilising its intricate life cycle as a model for chromatin dynamics in transcriptional regulation and using the Plasmodium specific histone variants H2A.Z and H2B.Z to understand the influence of histone variants on nucleosome stability and positioning.

Wir benötigen Ihre Zustimmung zum Laden der Übersetzungen

Wir nutzen einen Drittanbieter-Service, um den Inhalt der Website zu übersetzen, der möglicherweise Daten über Ihre Aktivitäten sammelt. Bitte überprüfen Sie die Details in der Datenschutzerklärung und akzeptieren Sie den Dienst, um die Übersetzungen zu sehen.